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& Banks, G
At present, some phage cocktails are available commercially and are currently used as either food additives or GRAS, such as ListShield and PhageGuard Listex P100
Grasa Localizada
The metabolic pathway of TMAO involves multi-organ coordination: dietary choline, carnitine, and other quaternary ammonium-containing compounds are metabolized by gut microbiota to produce trimethylamine (TMA), which is subsequently oxidized to TMAO by hepatic flavin-containing monooxygenases (FMOs) and primarily cleared by the kidneys (170)
The brain is particularly vulnerable to oxidative stress due to its high metabolic rate and relatively limited antioxidant defences
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