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The current findings have subsequently been supported by results from the phase II dose-finding trial with oral semaglutide in subjects with T2D [10]

Glucagon suppression : Reduces glucagon secretion, decreasing hepatic glucose production

However, semaglutide slows gastric emptying and reduces appetiteeffects that may mask symptoms of thyroid dysfunction, such as hunger changes or gastrointestinal distress

Use R73.03 when the patient is in a prediabetic state but has not yet been diagnosed with diabetes

Trial REIMAGINE 2 Phase 3 Duration Reported 2026 Population (N) Adults with T2D Key Result Sponsor reported HbA1c reduction of 1.91 percentage points and 14.2% weight loss