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This method accurately identifies the characteristic ion peaks of 5amino1mq and effectively eliminates interference from excipients and impurities

First, we performed extracellular flux analysis to assay the mitochondrial complex-dependent OCR profile in saponin-permeabilized Gclc fl/fl and Gclc fl/fl Mb1-Cre + FoB

The absence of MZB-mediated immunity was substantiated by the lack of anti-TNP IgM at 7 days post-immunization with TNP-Ficoll in Gclc fl/fl Mb1-Cre + mice (Supplementary Fig

The overall orientation shifted from CuA towards the L4 region

Altogether, as proposed in the model in Figure 8 , we conclude that the protein-reactive QIs of AQ mainly trigger ER stress, eventually leading to apoptosis in HepG2 cells