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In cases of significant level disturbances, nausea, vomiting, drowsiness or confusion have been reported, together with abnormal test results (for example, elevated transaminases)

0.085.0 mg0.125 mg5.0 mg(cagrilintide)0.08 mg(cagrilintide)0.125 mg(cagrilintide)0.25 mg(cagrilintide)0.3 mg(cagrilintide)0.4 mg(cagrilintide)0.5 mg(cagrilintide)0.6 mg(cagrilintide)0.7 mg(cagrilintide)0.8 mg(cagrilintide)0.85 mg(cagrilintide)0.9 mg(cagrilintide)1.0 mg(cagrilintide)1.1 mg(cagrilintide)1.2 mg(cagrilintide)1.3 mg(cagrilintide)1.4 mg(cagrilintide)1.5 mg(cagrilintide)1.6 mg(cagrilintide)1.7 mg(cagrilintide)1.8 mg(cagrilintide)1.9 mg(cagrilintide)2.0 mg(cagrilintide)2.1 mg(cagrilintide)2.2 mg(cagrilintide)2.3 mg(cagrilintide)2.4 mg(cagrilintide)2.5 mg(cagrilintide)2.6 mg(cagrilintide)2.7 mg(cagrilintide)2.8 mg(cagrilintide)2.9 mg(cagrilintide)3.0 mg(cagrilintide)3.1 mg(cagrilintide)3.2 mg(cagrilintide)3.3 mg(cagrilintide)3.4 mg(cagrilintide)3.5 mg(cagrilintide)3.6 mg(cagrilintide)3.7 mg(cagrilintide)3.8 mg(cagrilintide)3.9 mg(cagrilintide)4.0 mg(cagrilintide)4.1 mg(cagrilintide)4.2 mg(cagrilintide)4.3 mg(cagrilintide)4.4 mg(cagrilintide)4.5 mg(cagrilintide)4.6 mg(cagrilintide)4.7 mg(cagrilintide)4.8 mg(cagrilintide)4.9 mg(cagrilintide)5.0 mg(cagrilintide)In some embodiments, the extractable volume corresponds to a dose of about 0.08 to about 5.0 mg, such as a dose of about 0.125 mg to about 5.0 mg of cagrilintide

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The C18 fatty diacid side chain must be synthesized separately and then chemically conjugated to a specific lysine residue on the peptide backbone through a glutamic acid linker