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The study cohort was derived from the Semaglutide Treatment Effect in People with Obesity (STEP) 9 trial, a multicentre (61 sites across 11 countries) long-term Semaglutide assessment adopting double-anonymized, randomized, placebo-controlled study methodologies

These results strongly support the need for larger, randomized clinical trials to confirm these effects and explore the potential of repurposing GLP-1 RAs as a novel treatment for reducing harmful alcohol consumption

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Slowing titration or pausing dose increases for a few weeks can restore balance