Jaeschke H, Adelusi OB, Akakpo JY, Nguyen NT, Sanchez-Guerrero G, Umbaugh DS, Ding WX, Ramachandran A (2021) Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls
15 While rasburicase use is contraindicated in patients with G6PD deficiency, the acute risk of morbidity and mortality associated with untreated TLS creates a clinical dilemma
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Clinical studies highlight that participants experienced a 1520% reduction in body weight over 72 weeks, which translates to substantial weight loss