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Chronic low-grade inflammation further induces persistent microglial activation and polarization shifts, BBB endothelial dysfunction, and mitochondrial energy metabolism abnormalities, exacerbating neuronal damage [30]

pylori deliver its cytotoxin-associated gene A (CagA) protein via a type 4 secretion system (T4SS), directly linking this mechanism to the development of gastric cancer (172)

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The transcriptional signatures identified in GLP-1MK-801-treated animals were enriched for functional terms related to synaptic transmission, such as postsynaptic density and glutamatergic synapse (Fig

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