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However, people with severe liver disorders could have a higher chance of complications such as dehydration or gallbladder issues

Bruton's tyrosine kinase inhibitors: a new generation of promising agents for multiple sclerosis therapy

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These concerns first gained prominence around 20112013, when regulatory agencies began investigating potential pancreatic safety signals associated with incretin-based therapies, including both GLP-1 receptor agonists and DPP-4 inhibitors