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Retatrutide is still an investigational peptide that has not yet completed the full FDA review process to establish its long-term safety and effectiveness profile
Its development is linked to an imbalance in gut microbiota, which triggers the activation of harmful T cells
With a full understanding of the mothers health and breastfeeding goals, the right balance can be found
Most were mild to moderate and tended to occur during dose increases, similar to the pattern seen with semaglutide and tirzepatide.[1] A finding worth flagging: in the obesity trial, retatrutide produced small increases in heart rate (about 5 to 7 beats per minute on average at the higher doses).[1] Heart rate increases have also been seen with other drugs in this class, but the size in retatrutide was on the higher end
Zhang D, Xi Y, Boffa DJ, Liu Y, Nogueira LM
