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(PubMed) Heude B, Ducimetiere P, Berr C

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Prompt medical evaluation is important if symptoms include: Difficulty breathing at rest Inability to lie flat comfortably Chest pain Rapid or irregular heartbeat Swelling in one leg Symptoms worsening progressively over days or weeks These findings may indicate serious cardiac, pulmonary, or vascular conditions beyond Lyme disease

Because cysteine availability is the principal bottleneck in glutathione synthesis, increasing intracellular cysteine supply drives higher GSH production

[] Peripheral hormones critically influence these central regulatory pathways [Figure 3]