This figure, drawn from the original plasma studies following GHK-Cus identification, has become the standard reference point in the literature whenever researchers discuss the peptides relationship to aging
Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis
However, when taking a GLP-1 receptor agonist like Ozempic (semaglutide), this reflex can feel significantly more intense
We excluded 1) those with diagnoses of AF, atrial tachycardia, ventricular tachycardia, ventricular fibrillation, mechanical valve, hyperthyroidism, or mitral stenosis before or on the index date, 2) those with cardiac events (i.e., myocardial infarction, percutaneous intervention, valve/bypass surgery) in the preceding 3 months, 3) those currently receiving antiarrhythmic medications (e.g., amiodarone, dronedarone, flecainide, propafenone, or dofetilide) on the index date, 4) those who used insulin within one year prior or on the index date, and 5) those who do not have hemoglobin A1C (HbA1c) within one year prior or on the index date (eFigure 1)
If a platform is selling it to you, that is a red flag about the rest of their clinical practice