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Hypoxia, a pathological feature of endometriosis, stabilizes EZH2 mRNA by reducing m 6 A RNA methylation through increased ALKBH5 (m 6 A demethylase) and decreased YTHDF2 (m 6 A reader), thereby enhancing EZH2 protein levels

Elevated Gln/Glu was also found in the frontal cortex of the Gclm / mouse relative to controls [82, 84], which is further accentuated by social isolation stress after weaning [76]

This suggests IN delivery lowers mitochondrial metabolic load and shifts the hippocampus into a resilient, low-stress state

P., Lionetti, L., Crezcenzo, R., Botta, M., Barletta, A., & Liverini, G