Full-length APP, APP CTFs (C99) and endogenous BACE1 levels in the cortex (a and b) and the hippocampus ( e and f) were detected
Heavier, longer, or more frequent periods: Likely mechanism: estrogen release from adipose tissue Typical timeline: starts week 2 to 6, peaks around week 8 to 12, resolves by week 20 to 24 Associated findings: weight loss exceeding 1.5% per week, reduction in waist circumference What it means: your body is releasing stored estrogen faster than your liver can clear it Management: usually self-limiting
BM: Conceptualization, Data curation, Investigation, Methodology, Writing original draft, Writing review & editing
This is another reason providers transition patients to higher concentration vials as they titrate up
The damaging chemicals (free radicals) the body creates as a consequence of metabolism are what the term oxidative stress refers to