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Importantly, NAD + was systemically lowered, detectable in the blood of the patients

Statistical significance was assessed by two-way ANOVA followed by dks multiple comparisons (n = 6 technical replicates)

The transient nature of blood pressure changes, combined with the on-demand dosing strategy, mitigates concerns about sustained cardiovascular effects during long-term use

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Ni says its never been shown in large studies to improve a persons risk for heart disease or lower their risk of dying from cardiovascular causes