Am Health Syst Pharm 62:173181 Elbrnd B, Jakobsen G, Larsen S et al (2002) Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose of NN2211, a long-acting glucagon-like peptide 1 derivative, in healthy male subjects
These include regulation of mechanisms controlling reactive oxygen species (ROS), which cause macromolecular damage 16,17 , mitochondrial turnover or mitophagy 18 , and the mitochondrial unfolded protein response (UPR mt ), in which mitochondrial damage can be prevented by the removal of aggregated or unfolded proteins 19
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Springer Nature Singapore, Singapore Leiter O, Walker TL (2019) Platelets: the missing link between the blood and brain