According to the authors, boosting GSH status beneficially upregulates the genes of VD metabolism and VDR, both of which are needed to increase the bioavailability and blood levels of 25(OH)VD and reduce inflammation levels. They also found that co-supplementation with vitamin D and L-cysteine resulted in the upregulation of vitamin D regulatory genes and boosted vitamin D levels in the blood, as well as reduced inflammation and insulin resistance each with higher success compared to supplementing with vitamin D alone
The serum was immediately separated by centrifugation at 3000 rpm for 15 min at 4 C and stored at 80 C
It will be important to follow up on these results and optimize the conditions that may allow for complete preservation of skeletal muscle mass and function during disuse, not just during the recovery period
Mounjaro may contribute to an increased risk for thyroid c-cell tumors, acute pancreatitis, gallbladder disease, hypoglycemia, acute kidney injury, severe GI side effects, hypersensitivity reactions, worsening of diabetic retinopathy if you have type 2 diabetes
2018 Jul 7;19(7):1987.