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If the duotherapeutic molecule in this study alters neural plasticity, it could potentially be more economical than current anti-obesity drugs that require regular dosing

A different randomized trial of exenatide (a GLP-1RA sold as Byetta or Bydureon) in Parkinsons patients also showed benefit, and the effects persisted even after a washout period following treatment

Lilly said Thursday that patients on the amylin agonist shed 20% of their weight in a mid-stage trial

These GLP-1 drugs, including semaglutide and tirzepatide, have shown 15-25% body weight reduction in clinical trials, approaching the effectiveness of surgery