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10.1002/ajmg.a.38494 72 Di CostanzoA.AngelicoR

To evaluate the ability of molecules to interfere with aggregation of hCC while informing about cellular toxicity, cells were generated that produce and secrete WT and L68Q-hCC producing high-molecular weight complexes formed from the mutant protein

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As the oxidative burden on the mitochondria is lifted, these organelles can begin to shift away from inefficient anaerobic glycolysis (which produces the brain-fog-inducing lactate) and back toward efficient aerobic ATP production