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The review delves into the intricacies of different modification approaches, including N and C-terminal modifications, Fatty acid Side chain Modifications, and Large Molecule Conjugation Modifications, highlighting their rationale and resulting improvements in half-life, stability, receptor binding, and bioactivity
Funding We thank Princess Nourah Bint Abdulrahman University Researchers Supporting Project number (PNURSP2026R484), Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia
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Pharmacologic approaches to glycemic treatment: Standards of Medical Care in Diabetes2022 A
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