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In the Billon 2023 study, 50 mg/kg twice daily for 28 days increased succinate dehydrogenase-positive oxidative muscle fibers and raised OXPHOS complex protein levels
Notably, clinical improvements in skin lesions have been observed in some studies, independent of weight loss or glycemic control
Beyond its role as a direct physical scavenger of free radicals, lycopene acts as a sophisticated signaling molecule that actively upregulates the body's endogenous (internal) defense systems
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