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Both can become depleted through poor diet and aging
Because food stays in your stomach longer, you feel fuller faster and stay full for longer periods
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164,165,166,167 Similarly, DNA damage induces the relocalization of NAD + -dependent deacetylase SIRT1 to DNA breaks, which promotes DNA repair via opening the chromatin and recruiting the main DNA repair factors including KU70, NBS1, WRN, KAP1, XPA and APEX1
As we age, NAD+ levels naturally decline, leading to fatigue, cognitive decline, and slower recovery
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