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International Journal of Environmental Research and Public Health, 13(11), 1503
Mood Changes and Fatigue Women with PCOS often experience mood swings, depression, anxiety, and low energy levels
August 6, 2025:S2468-6530(25)00355-0
Design In the obesity trial, 338 participants (mean age 48 years, 48% women, mean BMI 37.3 kg/m 2 ) were randomised (2:1:1:1:1:2:2) to retatrutide 1 mg, 4 mg (titration), 4 mg (no titration), 8 mg (slow titration), 8 mg (fast titration), 12 mg or placebo over 48 weeks [45]
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