Neutrophils, eosinophils, and macrophages are the principal actors in promoting the inflammatory response
The Finkley 2005 study on 67 women aged 50 to 59 reported improvements in laxity, clarity, firmness, fine lines, wrinkles, and pigmentation across the face after 12 weeks
Temporary dose reduction during illness or significant life stress is reasonable, with resumption of escalation once circumstances normalize
Over the following weeks most people notice better skin hydration and texture first, plus subtle sleep and energy gains from Epitalon (weeks 13), then visibly firmer, smoother, more even skin (weeks 36), then deeper rejuvenation, elasticity, sometimes thicker hair and nails, with telomere support well established (weeks 612+)
I train four days a week and the soreness that used to linger three or four days after a session started clearing in about two