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Disrupting G6PD-mediated redox homeostasis enhances chemosensitivity in colorectal cancer

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Network construction Transcriptional similarities between diseases were calculated using three gene sets: (i) all annotated genes, (ii) the union of genes with significant differential expression (sDEGs), and (iii) the intersection of sDEGs, following previous studies on the molecular bases of comorbidities 14,15 (see Fig

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