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Together, these findings reveal a functionally relevant cell type-specific mechanism underlying the suppressive effects of GLP-1R agonists on cocaine seeking and highlight an endogenous GLP-1-expressing circuit that could be targeted to treat CUD and reduce cocaine relapse

CJC-1295 : CJC-1295, particularly with DAC, has an extended half-life, meaning that a single dose can elevate GH levels for up to a week

PMC 4423164

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It suppresses glucagon release, reducing the liver glucose output