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PD is the second most common NDD and is characterized by progressive loss of dopaminergic and specific non-dopaminergic neurons and the presence of Lewy bodies, which mainly consist of abnormally aggregated -synuclein
These include: Those with a history of cancer: IGF-1 can be involved in the growth of certain types of cancer
We also provide an update on the targets and clinical prospects of different antioxidants (melatonin, N-acetylcysteine, vitamins, -lipoic acid, mineral elements, phytochemicals, nutritional antioxidants, cytoprotectants and synthetic compounds) in the treatment of CIPN with the help of preclinical and clinical studies, emphasizing the great potential of antioxidants as adjuvant strategies to mitigate CIPN
However, an increase in demand has caused drug shortages, prompting companies to expand their capacity
That does not mean every reported benefit is false, but it does mean caution is necessary
