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In rodents, the enzyme long-chain acyl-CoA dehydrogenase (LCAD) can take over part of the VLCAD function, but in humans LCAD makes little contribution to lcFAO [6]
Serotonin connects to reward pathways by playing a regulatory role in the brains reward system, where it interacts with dopamine to influence behaviors tied to pleasure and reinforcement , as explained in a study by Harvard Brain Science Initiative titled Exploring How Serotonin and Dopamine Interact. While dopamine directly activates the reward pathway, triggering sensations of pleasure when we engage in rewarding activities, serotonin helps to modulate this pathway, maintaining balance
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10.1073/pnas.1313753110 7 BrutigamL.SchtteL
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