Future decision-making frameworks based on phenotype stratification and Bayesian integration should prioritize identifying who requires long-term maintenance versus a short-term window, and how to minimize the reproductive costs of post-discontinuation rebound
12881298, pubmed.ncbi.nlm.nih.gov/39401279/, Rossi, Giada, et al
Borneol exerts its antipruritic effects by inhibiting TRPA1 and activating TRPM8
doi: 10.3390/ijms26010380 27 BansalSSrinivasanSAnandasadagopanSRoy ChowdhuryASelvarajVKalyanaramanBet al
Subsequently, Moore proposed the hypothesis that intestinal secretions might have a glycemic-lowering effect in diabetics, which was the first study to suggest an effect of intestinal secretions on blood glucose (Moore, 1906), and in the 1960s a team of researchers in the UK and the US independently discovered the incretin effect, in which oral glucose markedly stimulates insulin secretion, setting the stage for the subsequent development of incretin (Elrick et al., 1964