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Disclosure statement Craig Russell does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment

The injections, Tirzepatide and Semaglutide, are pharmaceutical treatments administered via subcutaneous injection to aid in weight loss

Importantly, while weight loss was observed in these trials, the degree of improvement in cardiac outcomes were often disproportionate to the weight reduction alone, suggesting at weight loss-independent mechanisms 30,31,44

Medical clinics and med spas often take very different approaches to care

A novel 5HT3 receptor-IGF1 mechanism distinct from SSRI-induced antidepressant effects