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Researchers comment that a single introduction of the peptide may upregulate growth hormone production by somatotrophs for prolonged periods of time, thus apparently contributing to an overall increase in [growth hormone] secretion by 46% and also potentially upregulating its main anabolic mediator insulin-like growth factor-1 (IGF-1) by 45% on average

The rationale is that their mechanisms are additive: local repair support plus systemic cell mobility

The rabbits were euthanized via carbon monoxide inhalation nine weeks after the first collagenase injection for subsequent examination [1]

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