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It also plays a role in energy homeostasis and cellular metabolism

While routine vitamin B12 monitoring is not specifically mandated in tirzepatide prescribing information, clinical judgment should guide individualized screening strategies based on patient risk factors and clinical presentation

Blood chemistry panels showed no hepatotoxicity (ALT, AST, bilirubin all within normal limits), no nephrotoxicity (creatinine, BUN unchanged), and no hematologic changes

Precautions General Doses of vitamin B12 exceeding 10 mcg daily may produce a hematologic response in patients who have a folate deficiency

Conclusion Though not perfect, the no longer available Schillings test presented a useful option for judging the uptake of B12 and for clarifying whether an impaired uptake was caused by the lack of intrinsic factor