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Urate reabsorption is coupled to renal lactate reabsorption at the apical membrane of the proximal tubule via interactions between SLC22A12 and the lactate transporters encoded by the SLC5A8 and SCL5A12 genes
Being mindful of all pharmacology and vaccines Antacids (deplete B12) Cholestyramine (deplete cobalamin and folate absorption) common in gallbladder issues during pregnancy
Dosages used in the reviewed studies ranged from 600 to 3600 mg per day for 8 weeks to 1 year, with studies using dosages of 10002000 mg per day showing the best responses
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