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Clinical trials of GLP-1-based therapies commonly exclude individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) on the basis of preclinical thyroid C-cell findings
Because tirzepatide is approved and widely available, it has accumulated a large amount of real-world safety and efficacy data
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A comparative study of amino acid consumption by rat islet cells and the clonal beta-cell line BRIN-BD11 - the functional significance of L-alanine
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