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Both GLP-1 and GIP recruited Venus-mG s to their NLuc-labeled receptors in a dose-dependent manner
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A breach results in the release of apoptotic molecules, such as cytochrome c (CYCS), apoptosis-inducing factor mitochondria-associated 1 (AIFM1), and diablo IAP-binding mitochondrial protein (DIABLO/SMAC) [112]
Abbreviations NAION: Nonarteritic anterior ischemic optic neuropathy RAPD: Relative afferent pupillary defect ODD: Optic disc drusen GLP-1 RA: Glucagon-like peptide-1 receptor agonist OCT: Optical coherence tomography ETDRS: Early Treatment Diabetic Retinopathy Study BMO: Bruchs membrane opening VA: Visual acuity IOP: Intraocular pressure GCA: Giant cell arteritis SAP: Standard automated perimetry MD: Mean deviation GCL: Ganglion cell layer EDI-OCT: Enhanced depth imaging optical coherence tomography VF: Visual field References Salvetat ML, Pellegrini F, Spadea L, Salati C, Zeppieri M
The mean starting A1c was 8.5%
