glp-1 for nash Effects of receptor agonists on the degree of liver fibrosis and CRP in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: A systematic review and meta-analysis Frontiers | Future Perspectives on

A dual GLP-1-estrogen conjugate (GE) designed to selectively deliver estrogen to GLP-1R + cells induced substantial weight loss in mice without evidence of systemic estrogenic effects, as assessed by uterine weight and growth of estrogen-dependent breast cancer xenografts (Kanoski et al., 2011)

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The study examined results for over 59,000 patients and found no difference in rates of suicidal ideation/attempt/completion or self-harm between drug recipients and those receiving placebo