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Importantly, despite the existing evidence for low-level protein translation in erythrocytes [41], protein synthesis in mature erythrocytes is negligible or virtually absent, and erythrocytes cannot regulate cell death by production of cell death-associated proteins

Retatrutide targets appetite and energy pathways, while MOTS-c supports mitochondrial function and glucose metabolism

This framework is intended as a conceptual guide rather than a deterministic regulatory algorithm

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