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Motor cortex is isolated from P3 pups of WT-eGFP and and prpTDP-43 A315T -UeGFP mice, and dissociated cells are plated on glass coverslips to establish motor cortex cultures in vitro 32

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In most adult somatic cells, telomerase activity is very low or absent, allowing telomere shortening to proceed unchecked

Retinol works by speeding up cell turnover, which can improve texture and reduce fine lines