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Chronic fatigue (anecdotal): Many with ME/CFS report problems with mast cell activation or histamine intolerance symptoms
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both drugs are made by Eli Lilly, and the company has positioned them as complementary rather than competitive: tirzepatide for patients needing maximum weight loss, and orforglipron for patients preferring oral therapy or as a maintenance option after injectable treatment
Fat will feel like a pocket & often create a bulge or roll when grabbed, whereas loose skin will be stretchy & thin between the fingers & can be rolled or rubbed against each other with no substance in between
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