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GLP-1 receptor agonists were initially developed to improve glycemic control in type 2 diabetes by enhancing insulin secretion and inhibiting glucagon release, with additional effects on appetite regulation and gastric emptying later recognized as clinically relevant (Meloni et al

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Consequently, obesity also appears to increase liver-specific mortality, even in children ( 24 )

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Study Details: The data used by the researchers was sourced from TriNetX, a large database with information on approximately 127 million patients from 15 countries, predominantly the United States