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But hair follicles have insulin receptors and respond to insulin-like growth factor 1 (IGF-1)
The therapeutic effects of central leptin gene therapy have been reported in insulin-deficient diabetes and in obesity animal models, such as ob/ob, diet-induced obese mice, insulin-deficient type 1 diabetes mice, and insulin-dependent diabetes animals (Akita mice) (Dube et al., 2004, 2006
Reported side effects of DSIP are limited because there are very few human studies
B.WangQ.LongY.ChengZ.ChenS.ZhengH.et al
Insulin resistance is a major driver of fat buildup in the liver
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