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However, higher doses extend the duration of receptor occupancy and downstream signaling because more peptide molecules are available to bind receptors over the clearance window

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A clinical trial in 2015 linked an undisclosed GLP-1 to significant improvements in OSA severity, while a 2016 clinical trial found that weight loss resulting from liraglutide was significantly associated with a reduction in the apnea-hypopnea index (AHI)

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