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doi:10.1002/da.22854 Carpenter JK, Andrews LA, Witcraft SM, Powers MB, Smits JAJ, Hofmann SG

In vitro and animal studies have found that lipoic acid exhibits immunomodulatory properties through mechanisms that stimulate the production of cyclic AMP (cAMP) (90, 91) a central regulator of innate immune functions and inhibits the migration of immune cells into the brain and spinal cord (92), possibly by decreasing endothelial expression of cell adhesion molecules, inhibiting expression of enzymes like matrix metalloproteinases (MMP), and/or reducing the permeability of the blood-brain barrier (87, 89, 93, 94)

171,172 Moderate autophagy is a degradation system that maintains cellular homeostasis, 173 and cells can achieve renewal and avoid death through basal levels of autophagy

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But both Grunvald and Cardel agree that your specific supplement routine should be personalized and guided by a doctor or dietitian