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Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1

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In a Phase 2 trial published in the New England Journal of Medicine in 2023, participants lost up to 24.2% of their body weight over 48 weeks

2 The WHO and other global organizations advocate for a multi-pronged approach to prevent infections, including vaccination, sanitation, antimicrobial stewardship, and the development of new diagnostics and drugs