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Clinical investigations The first report on BDNF from studies in a clinical population came from Phillips and colleagues who found that BDNF mRNA was reduced in postmortem hippocampal samples obtained from AD patients, suggesting that BDNF may have contributed to the progressive atrophy of neurons in AD [132]
Endogenous Roles The compound performs three main functions: neutralizing reactive oxygen species, conjugating xenobiotics for Phase II detoxification (via glutathione S-transferases), and recycling other antioxidants such as vitamins C and E
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neuroendocrine disorders involving GH secretion rhythm disruption
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