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(2021) discovered that peripheral blood neutrophils from patients with active SLE had elevated levels of intracellular lipid peroxides and exhibited the typical morphological changes of ferroptotic cell death

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We next assessed whether FAK activation played a role in 25HC-mediated induction of the proinflammatory response by assaying secretion of the proinflammatory cytokines TNF- (TNF) and IL-6 in cells expressing FAK, as well as in cells in which FAK was absent or inhibited

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Which tissues respond best (muscle, endocrine, kidney, brain)