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Neuroinflammation Neuroinflammation, microglia activation in response to amyloid deposition, plays a central role in the pathogenesis of AD (30)

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the hippocampus was subdivided into three parts: one preserved at 80 C for gene expression analysis, another homogenized and stored at 20 C for evaluation of neurotrophic factors, enzymes, and oxidative stress markers, and a third fixed in 10% buffered formalin for histological examination

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