Comprising 39 amino acids, GLP-1-Ss relatively large structure enables it to stimulate insulin release from the pancreas by binding to both GIP and GLP-1-S receptors
doi: 10.1155/2016/2497348 63 LawsonNHsiehCMarchDWangX
While albiglutide demonstrated good glycemic efficacy and tolerability, adverse effects included upper respiratory tract infections, diarrhea, nausea, and injection site reactions
He, C., Tsend-Ayush, E., Myers, M
If the cell cannot recycle GSSG back into GSH fast enough using an enzyme called glutathione reductase, the cell enters a state of toxic oxidative stress, leading to mitochondrial damage and, eventually, programmed cell death (apoptosis)