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This multi-target design represents a significant advance beyond both the single-agonist GLP-1 receptor agonists (such as semaglutide) and the dual GIP/GLP-1 agonists (such as tirzepatide)

Conclusions During five years of observation of all persons with T2D in Denmark, use of once-weekly semaglutide independently more than doubled the risk of NAION

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It helps delay premature skin aging, prevents sun damage, and improves the appearance of wrinkles, dark spots, and acne

Rauch C et al