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All of these are weekly injections that help with weight loss by curbing appetite, but there are key differences: Active Ingredient: Mounjaro's active ingredient is tirzepatide, a dual GLP-1/GIP agonist, whereas Ozempic/Wegovy use semaglutide, a GLP-1 agonist only
In addition to the effects on weight loss and diabetes control both cardiovascular risk factors other mechanisms of action have been proposed for the entire class of GLP-1 agonists, Jayne Morgan, MD, a cardiologist and the executive director of Health and Community Education at the Piedmont Healthcare Corporation in Atlanta, GA, not involved in the study, told MNT
Researchers affiliated with a European weight management company also recently reported that slowly tapering off the medications may help maintain weight loss
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Going back to the STEP-UP trial with semaglutide it was seen in about 20% of patients in that trial as well on the 7.2mg dose
