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Pyocyanin, being a zwitterion, diffuses across the host cell membrane and undergoes redox reactions by accepting electrons from NADPH which it subsequently donates to molecular oxygen to form primarily O 2 - and subsequently H 2 O 2 through dismutation ( The results detailed in Figure 5 provide a means to explain the pyocyanin/GPx/GRed/GSH interplay: that is, pyocyanin increases the level of ROS, and this leads to enhanced GPx activity in A549 cells because GPx catalyzes the reaction through which GSH neutralizes H 2 O 2
Eat smaller meals: Focus on frequent, small portions instead of three large meals to avoid overfilling your stomach
Santos-Morales O, Daz-Machado A, Jimnez-Rodrguez D, Pomares-Iturralde Y, Festary-Casanovas T, Gonzlez-Delgado CA, et al
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